Nina Eriksson

Pregnancy and proctitis


The questioner is worried about safety of 5-ASA treatment while pregnant. I am happy to be able to write that there does not need to be worries about this treatment; not with suppositories or enemas neither with tablets. It is easier to get pregnant if the disease is in remission. It is also known that if the disease is in remission when getting pregnant the risk of a flare is only the same as in nonpregnant women. Quiescent disease during pregnancy has great impact on progression of pregnancy, duration of pregnancy and weight of the newborn. Children born to parents who are using 5-ASA do not have more malformations nor deformations than newborns of “healthy” parents. My warm advice is to continue with ongoing medication instead of reducing it in order to avoid relapses and taking the risk of activation of inflammation with consequences.